Explain why translesional synthesis is a DNA damage tolerenace mechanism rather than a DNA repair mechanism?

Answers

Answer 1

Proof Reading: while printing a page, the typesetter set the types and impression is taken, proofreading is done to correct mistakes if any, and the final printing is done. A similar follow-up mechanism is done after DNA synthesis. If DNA polymerase detects an incorrect nucleotide pair, it will remove and replace with the correct nucleotide immediately.

What is Mismatch Repair?

Mismatch Repair:even after DNA synthesis, mismatch area(insertion or deletion) can be identified on the newly synthesized DNA.

In the mismatch repair, specific proteins scan the newly synthesized DNA strand. The mismatch area is identified and loop.

The second protein complex remove the mismatch segment. Finally correct segment is synthesized by the help of DNA polymerase, SSBs and ligase.

DNA damage repair mechanism: when DNA get damaged, there's a repair process that fix the damage. This includes Direct reversal, excision repair and Double-stranded break repair.

Thus, this could be the answer.

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Related Questions

A baby born 39 weeks after conception and weighing 3,400 grams would be characterized as __________.

Answers

Answer:

neither preterm nor small-for-gestational-age

Explanation:

A baby born 39 weeks after conception and weighing 3,400 grams would be characterized as neither preterm nor small-for-gestational-age. The correct option is b.

What is considered as preterm?

Preterm and premature are synonyms for "early." Preterm labor is defined as labor that begins before 37 weeks of pregnancy.

Labor is the process by which your body gives birth to your baby. Premature labor can result in premature birth. Premature birth occurs when your baby is born before the 37th week of pregnancy.

Premature babies are those who were born more than three weeks before their expected due date and did not have enough time to grow and develop as much as they should have before birth.

Chronic stress, in particular, can increase your chances of having a small baby or going into premature labor, also known as preterm labor.

Thus, the correct option is b.

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Your question seems incomplete, the missing options are:

a.) both preterm and small-for-gestational-age

b.) neither preterm nor small-for-gestational-age

c.) small-for-gestational-age only

d.) preterm only

which woudl be included in the plan of care for an obstetrical client who has been taking carbamezepine

Answers

The evaluation for neural tube defects should be included in a patient that took carbamazepine throughout the first trimester of pregnancy.

What is Carbamezepine?

Carbamazepine may be characterized as an anticonvulsant medication often operated for the remedy of epilepsy and neuropathic ache provoked by diabetes.

Carbamazepine has newly been determined to have a proliferation threat of genetic malformations and neurodevelopmental irregularities, at the time of pregnancies.

Therefore, the evaluation for neural tube defects should be included in a patient that took carbamazepine throughout the first trimester of pregnancy.

The complete question is as follows:

Evaluation of fetal hydramnios. Evaluation for neural tube defects.Evaluation of cardiac malformation.Chromosomal assessment for down syndrome.

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A person drops off a prescription for a beneficiary who is a regular customer. The prescription is for a controlled substance with a quantity of 160. This beneficiary normally receives a quantity of 60, not 160. You review the prescription and have concerns about possible forgery. What is your next step?.

Answers

Calling the prescriber to verify the quantity is the next step to ascertain if it's forgery.

What is Forgery?

This involves imitating a copy of a material with the sole intent of defrauding people.

The error of 60 instead of 160 means the prescriber must be called to verify the exact amount of prescription packaged.

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If you want to know if Vitamin D would help sick people get better faster, the independent variable would be:

Answers

If you want to know if Vitamin D would help sick people get better faster, the independent variable would be the number of people on the group.

What is an independent variable?

It should be noted that an independent variable means the variable that stands alone and isn't changed by the other variables.

In this case, if you want to know if Vitamin D would help sick people get better faster, the independent variable would be the number of people on the group.

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During an instruction session on breast self-examination, the nurse would instruct a client to perform the exam at which time

Answers

The nurse would instruct a client to perform the exam a week after the period ends.

Who is a nurse?

It should be noted that a nurse simply means an individual who is in charge of looking after the health of an individual.

In this case, the nurse would instruct a client to perform the exam a week after the period ends.

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immediately after recieving spina anesthesia, a client develops hypotension. Which action will the nruse anticipate needing to take

Answers

When the client experiences hypotension, the action by the nurse will be to place the client in a trendelenburg position.

What is a trendelenburg position?

It should be noted that a trendelenburg position is the position for a patient on the operating table especially during surgeries.

In this case, when the client experiences hypotension, the action by the nurse will be to place the client in a trendelenburg position.

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where should you begin the primary assessment of a patient displaying a psychiatric issue?

Answers

You should begin the primary assessment of a patient who has a psychiatric problem with an interview to get to know the patient.

How to evaluate a psychiatric patient?

In the psychiatric evaluation, an interview is initially carried out to get to know the patient and, if necessary, a conversation with other sources, such as

family membershealth professionalssocial workersamong others, can be requested.

With this information, we can conclude that you should begin the primary assessment of a patient who has a psychiatric problem with an interview to get to know the patient.

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Professional practice involves applying the knowledge of kinesiology in a work setting. Group of answer choices True False

Answers

Answer:

The correct answer is "True"

Explanation:

The responsibility for you developing into a marketplace Profesional falls primarily in your own shoulders.

what is medicare annual enrollment period

Answers

Answer:

When you can get medicare.

Explanation:

When you first become eligible for Medicare, you can join a plan. Open Enrollment Period. From October 15 – December 7 each year, you can join, switch, or drop a plan. Your coverage will begin on January 1 (as long as the plan gets your request by December 7).

Answer:

October 15 - December 7.

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A client comes to the emergency department following an assault and is extremely agitated, trembling, and hyperventilating. Which initial nursing action is appropriate

Answers

The initial nursing action that is appropriate is to remain with the client until the anxiety reduces.

Who is a nurse?

A nurse simply means the individual in a hospital or clinic that looks after the patient.

In this case, the client comes to the emergency department following an assault and is extremely agitated, trembling, and hyperventilating. It's important for the anxiety to reduce.

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Ms. O’donnell learned about a new ma-pd plan that her neighbor suggested and that you represent. She plans to switch from her old ma hmo plan to the new ma-pd plan during the annual election period. However, she wants to make sure she does not end up paying premiums for two plans. What can you tell her?.

Answers

She should consult her physician and insurance company in charge of the plan in this scenario.

What is Insurance?

This is the means of protection from any form of loss or theft and comprises of different types such as medical etc.

The physician and insurance company will have to liaise with one another to prevent double payment by the client.

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Answer:

Explanation:

She only needs to enroll in the new MA-PD plan and she will automatically be disenrolled from her old MA plan.

which is included in the care of a newborn infant whose mother has had untreated syphilis since the second trimester of pregnancy

Answers

The infant should be screened immediately to determine whether treatment is necessary.

What is syphilis?

The disease called syphilis  is a se-xually transmitted infection that is common in many adults. It could lead to several congenital problems when mothers have untreated syphilis.

The care that should be included for a newborn infant whose mother has had untreated syphilis since the second trimester of pregnancy is that the infant should be screened immediately to determine whether treatment is necessary.

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Is a freestanding cabinet that is used to hold something

Answers

Answer:

The answer would be a console

The type of stretching in which a person performs a movement and holds it for a set amount of time is called

Answers

Active stretching, or static active stretching.

A client is admitted for a transurethral resection of the prostate (TURP). Preoperative teaching will include which information

Answers

Preoperative teaching will include the epidural or spinal anesthesia which will be administered to the patient.

What is preoperative teaching?

It should be noted that preoperative teaching is the program of instruction that should be based on one's learning needs.

In this case, preoperative teaching will include the epidural or spinal anesthesia which will be administered to the patient.

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What is the primary mechanism for maintaining homeostasis?

Answers

Answer: Negative feedback

Explanation:


Your patient needs to have their vitals checked before leaving the facility. The policy is that only nurses can perform this activity, and the two on shift today
are currently busy doing paperwork. Your patient has been in the clinic for several hours and is anxious to leave.

Answers

The nurses should stop the doing the paperwork and go attend to those patient if it seems forever finishing the paper and then come back to it later. it would be very annoying to have to wait a long time before the nurses attend to you and that might end up pushing those patents away from that hospital because then those patients would think they don't attend to them fast and may even end up causing a bad name for the hospitals.

What should be included in the change of shift report?

It should have the patient's medical record, current medication, allergies, pain levels and pain regime plan, and discharge instructions.

Providing these sorts of pieces about your patient in your end of shift report decreases the risk of an oncoming nurse putting the patient in danger.

Thus, this could be the answer.

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Health issues can be addressed in part by the ________ made by doctors and researchers that can help people live longer, healthier lives.

Answers

Health issues can be addressed in part by the medical advances made by doctors and researchers that can help people live longer, healthier lives.

What is health?

It should be noted that health simply means a physical, mental, and social well being of an individual.

In this case, health issues can be addressed in part by the medical advances made by doctors and researchers that can help people live longer, healthier lives.

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hich condition would require an adjustment in the recommended intake of protein that differs from the RDA

Answers

Question:

a. diabetes

b. osteoporosis

c. kidney disease

d. stroke

e. heart disease

Kidney disease condition would require an adjustment in the recommended intake of protein that differs from the RDA.

What does "recommended dietary allowance" refer to?

The Food and Nutrition Board has determined the levels of essential nutrient intake known as Recommended Dietary Allowances (RDAs) to be sufficient to meet the known nutrient needs of nearly all healthy individuals.

For those unable to excrete nitrogenous wastes, such as those with severe liver disease or renal failure, protein restriction is employed.

A healthy adult weighing 75 kg has a protein RDA of 60 g (0.8 g/kg x 75 kg = 60 g) because the RDA for protein for an adult is 0.8 g/kg.

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When helping a pregnant woman with a drinking addiction you should not: Group of answer choices expect instant success be a cheerleader for her encourage her to talk with her health care provider talk on the phone with others for support

Answers

Answer:Alcoholism is a difficult disease, which includes both a psychological and physical dependence. It cannot be fixed overnight, even if a woman is pregnant. You should be a cheerleader for her and encourage her to talk to her doctor. You should also have a support system of your own, and talk on the phone with loved one when you need to, while respecting her privacy as well.

Explanation:

which type of drug classification are addictive drugs that have an extremely relaxing effect?

Answers

The type of drug classification are addictive drugs that have an extremely relaxing effect are depressants.

What are depressants?

It should be noted that depressants are the drugs that slow down the activities in the central nervous system of the body.

In this case, the type of drug classification are addictive drugs that have an extremely relaxing effect are depressants.

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Claustrophobia and acrophobia are classified under which of the following types of anxiety-related disorders?

A.Social anxiety disorders

B.Specific phobia

C.Obsessive-compulsive disorders

D.Agoraphobia

Answers

Anwser:

A: Social anxiety disorders

Explanation:

Agoraphobia: a fear of open spaces

Claustrophobia: a fear enclosed spaces

The Dietary Reference Intakes (DRI) committee recommends a diet that provides _____ percent of its calories from carbohydrate.

Answers

Answer:

45% to 65%

Explanation:

The Dietary Guidelines for Americans recommend that carbohydrates make up 45% to 65% of total daily calories. So if you get 2,000 calories a day, between 900 and 1,300 calories should be from carbohydrates.

Probably the most common disrupter of sleep is Group of answer choices sleep apnea. restless leg syndrome. circadian rhythm problems. a stressful lifestyle.

Answers

restless leg syndrome, it can cause violent shaking and up to hours of no rest

The most common disrupter of sleep among the given choices is sleep apnea. The correct option is A, Sleep apnea.

Sleep apnea is a sleep disorder characterized by pauses in breathing or shallow breaths during sleep.

Sleep apnea often leads to fragmented and disrupted sleep, as the pauses in breathing can cause brief awakenings or arousals from sleep.

There are three main types of sleep apnea:

Obstructive Sleep Apnea (OSA): This is the most common form of sleep apnea. It occurs when the muscles in the throat relax during sleep, causing the airway to narrow or close completely. Central Sleep Apnea (CSA): Central sleep apnea is less common and occurs when the brain fails to send proper signals to the muscles responsible for controlling breathing. Complex/Mixed Sleep Apnea: Complex or mixed sleep apnea is a combination of both obstructive and central sleep apnea.

Restless leg syndrome (RLS) is another sleep disorder that can disrupt sleep, but it is less prevalent compared to sleep apnea.

Thus, the correct option is A, sleep apnea.

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why are individuals in many developing countries susceptible to diseases such as polio and pertussis

Answers

Answer:

Lack of education. They don't get vaccinated. Have not developed their medical systems as they are developing countries.

Rett syndrome results in severe neurological delays that cause children to be short, be thin-appearing, and _____.

Answers

Rett syndrome results in severe neurological delays that cause children to be short, be thin-appearing, and unable to talk.

What is Rett syndrome?

It should be noted that Rett syndrome is a genetic disorder that affects the way that the brain of an individual develops.

In this case, Rett syndrome results in severe neurological delays that cause children to be short, be thin-appearing, and unable to talk.

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Ongoing stress does not affect all aspects of your health Ongoing stress does not affect all aspects of your health True False

Answers

FALSE.... . ...........

A nurse is admitting a client to the palliative unit and discussing advanced directives. Which statement made by the client leads the nurse to believe the client requires clarification around advanced directives

Answers

The statement that is made by the client that led to the nurse to believe that client requires clarification is "This will stop my daughter-in-law from putting me in a home".

What are advanced directives?

Advanced directives are documents written and signed with the full knowledge of the patient or patient's relatives concerning the their health care decisions made about them ahead of time.

When such a statement as "This will stop my daughter-in-law from putting me in a home", being made by a client it shows they are yet to understand the meaning of advanced directives.

Therefore the nurse is meant to clarify them further.

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Difference between male and female pelvis

Answers

Answer:

The male pelvis is thicker and heavy while the females pelvis is thinner and lighter in weight.

Explanation:

Hope this helps :)

Answer:

male is thicker and heavy

A year ago, Tyree drank about one cup of coffee per day. Now, he needs four cups of coffee to receive the same effect. Tyree is experiencing: Please choose the correct answer from the following choices, and then select the submit answer button. drug withdrawal. drug sensitization. drug addiction. drug tolerance.

Answers

If Tyree now needs four cups of coffee to receive the same effect then it is an example of drug tolerance.

What is drug tolerance?

Drug tolerance is a physiological phenomenon where an individual must increase the amount of drug to have the same effect.

Drug tolerance is caused by the presence of more receptors in the brain that need to bind to the active principle of the drug.

In conclusion, if Tyree now needs four cups of coffee to receive the same effect it is an example of drug tolerance.

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Tyree is encountering a possibility of Drug tolerance. Thus, the correct option is D.

What is Drug toleration?

Drug toleration may be characterized as a pharmacological concept that transpires when the body acquires employed a medicine so that either more medicine is required or distinct medicine is needed to display the same influence.

Drug tolerance is an action that is adjudicated by several receptors which are present throughout the body. But the receptors of the central nervous system control or supervise the whole system's effectiveness.

Thus, it is well described above.

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9. Will the teacher test our English? Passive voice A decrease in the quantity supplied of iPads is caused by a(n) increase in TV advertising for iPads. increase in the number of iPad consumers. technological advancement in iPad production. drop in the price of iPads. which choices are equivalent to the expression 3 square root of 5 Without using the formula, work out the gradient of the graph shown. Give your answer in its simplest form? 28.6% of city employees ride the bus to work.Last year,29.7% of city employees rode the bus to work.What is the relative change from last year to this year Find the lengths of sides marked with variables (x, y, w, z). Show all work do trust-busters still exist today? If a counselor wants a person other than a biological parent or legal guardian (such as a step-parent or grandparent) to have confidential information regarding a minor client, a simple solution is to: Group of answer choices Why did Gregor Mendel choose to use purebred plants in his experiments?O They reproduce sexually.O They exhibit only one form of a traitO They have a variety of traits.O They reproduce asexually, A rectangular bedroom has an area of 117 ft. the length of the bedroom is 4ft more than the width. find the length and the width of the bedroom A violin sounds a note of F sharp, with a pitch of 370 Hz. What are the frequencies of the next three harmonics produced with this note? According to the World Health Organization, a BMI lower than ____ is an indication of malnourishment. How were enslaved africans treated upon arrival in the new world?. supposed an individual has a body fat percentage of 17.5% and weighs 164 lbs. how many pounds of his weight is made up of fat? round your answer to the nearest tenth. Use the drop down menu to complete the statements. Fossils on continents that are n W separated by Support the theory of the continental drift When downgrading a clients subscription, what will be affected as a result of the downgrade? Pls give me answerInitially, a box contains three white and five red balls. Ballsare drawn at random from the box. Whenever a red ball is drawn, it is placedback into the box together with one extra red ball. Whenever a white ball isdrawn, it is placed back into the box together with two extra white balls. Whatis the probability that the first three balls are drawn out of the box alternatedin colour? You are driving on a two-lane highway. The vehicle directly ahead of you has pulled out to pass the car ahead of them. It looks like they might not have enough room to complete the pass safely. You should A: Take your foot off the gas pedal and wait to see what happens before reacting further. B: Brake firmly and keep your vehicle in the middle of your lane. C: Immediately slow down and move closer to the right edge of the road. Look for an open area on your right, in case you must drive off the road to avoid a crash. On a coordinate plane, a dashed straight line has a positive slope and goes through (negative 3, 1) and (0, 3). Everything to the left of the line is shaded.Which linear inequality is represented by the graph?y 3/2x + 3y > 2/3x + 3y < 3/2x + 3 I need this to be solved please and thank you