Long-term toxicology of an experimental drug in animals most likely refers to which part of drug development?

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Answer 1

The long-term toxicology of an experimental drug in animals most likely refers to preclinical research in drug development.

What is drug development?

Drug development refers to the steps and procedure which are employed in developing and approving new drugs for use in treatment of diseases.

The steps in drug development include:

Discovery and Development.Preclinical Research.Clinical Research.FDA Drug Review.FDA Post-Market Drug Safety Monitoring

Preclinical research involves studies of the drug using animal models.

Therefore, the long-term toxicology of an experimental drug in animals most likely refers to preclinical research in drug development.

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Related Questions

a patient has a score of 1 on the modified borg scale. which stage of dyspnea does this represent?

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The stage of dyspnea for a patient who scored 1 on a Borg scale is very slight.

What is Borg scale?

The Borg Rating of Perceived Exertion (RPE) is a way of measuring physical activity intensity level.

Borg scale provides a measure of how hard it feels that the body is working based on the physical sensations that the subject experiences.

A rating of 20 on Borg scale is perceived as maximal exertion while a rating of 1 on Borg scale is perceived as very slight.

Thus, the stage of dyspnea for a patient who scored 1 on a Borg scale is very slight.

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A nurse evaluates a client with a temporary pacemaker. The client's ecg tracing shows each p wave followed by the pacing spike. What is the nurse's best response?

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The nurses best response should be to document the findings and continue to monitor the client.

What is a temporary pacemaker?

A temporary pacemaker is a device that is inserted into the heart that helps an abnormal heart beat to get back to a normal rhythm.

It is the work of a nurse to constantly monitor the electrocardiogram of the patient that is on temporary pacemaker.

Therefore, the nurses best response should be to document the findings and continue to monitor the client.

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which finding is expected in a pediatric patient with viral pneumonia?

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The major finding that is expected in a pediatric patient with viral pneumonia is an abdominal pain.

What is a viral pneumonia?

A viral pneumonia as the name implies is caused by a virus and a disease infected by the lung.

The common cause of viral pneumonia is common cold and flu. The major finding that is expected in a pediatric patient with viral pneumonia is an abdominal pain.

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Twisting of an organ or a structure on itself is ________.

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The twisting of an organ or a structure on itself is called Volvulus.

Volvulus can be described as a condition in which the intestines in the boy twist round each other thereby obstructing certain functions in the body.

The symptoms of volvulus in the body include;

-It could lead to vommiting of food particles
- It could lead to constipation
- It could lead to nausea
- It could lead to abdominal discomfort in the body

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Heidi sustained damage to her spinal cord in a car accident. She has no difficulty moving her arm, but has lost some sensation in her arm. What part of her spinal cord must have been injured?.

Answers

Heidi's posterior horn of spinal gray matter is the part of the spinal cord that must have been injured due to a car accident.

What is a Spinal cord?

A spinal cord may be defined as a portion of the central nervous system that sprints from the underside of the skull down to the epicenter of the back.

The posterior horn of the spinal gray matter involves the function of receiving sensory information from the body. Such as vibrations, adequate touch, proprioception, etc.

Thus, when a person loses the ability of sensation in her arm or any part of the body, it indicates that the posterior horn of the gray matter is functionally adversely.

Therefore, it is well described above.

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Which practice contributes the most to land pollution?
Which practice contributes the most to land pollution?
A.
disposal of industrial wastes and household garbage
B.
eating unhealthy food for convenience
C.
driving instead of using public transportation

Answers

Answer:

option A

Explanation:

A) disposal of industrial wastes and household garbage

A client who experienced shock remains unstable. Which medication classes would the nurse anticipate to be ordered to prevent or minimize stress ulcers? select all that apply

Answers

The medication class that can prevent or minimize stress ulcer is proton pump inhibitors.

What is stress ulcer?

Stress ulcer is defined as the break in the continuity of the mucosal lining of the gastrointestinal tract which occurs after shock, sepsis or trauma.

The class of drugs that can be used to minimise stress ulcer in unstable shock patients are proton pump inhibitors.

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A medical assistant is answering the clinic phone. Which of the following guidelines demonstrates professional telephone etiquette?

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Answer:

Answering the telephone in a professional manner involves answering within two to three rings, so the caller is not left waiting. If taking multiple calls, proper etiquette suggests that you give the first caller priority unless the second caller has an emergency.

Why are many crusty breads cooked in long, thin loaves?

Answers

Loaf pans are typically used to bake crisp-crusted loaves in order to get a desired crust.

Answer:

Crisp-crusted breads are usually baked in loaf pans in order to produce a desirable crust. Sourdough must be mixed for a long time, in order to reduce the stickiness of the dough. Refrigerating a sourdough starter has what effect? It slows fermentation.

a food worker has nasia and diharrea the night before she is sceduled to work the opening shift. if she feels better in the morning, what should she do

Answers

Answer:

DO NOT go into work the morning of after having symptoms as it can be contagious!!!!

Explanation:

When a food worker reports of having such symptoms as nausea or diarrhea, they must stay home and be excluded until the symptoms have been gone for a full 24 hours or until the employe brings a doctors notes stating that the condition is gone or not contagious. This needs to be done since they are working with food and a high level of contamination it need to be sure and safe that their problem isn’t contagious for the rest of the employee’s and the customers themself.

Nationally there are approximately __________ persons arrested for dwi

Answers

Nationally there are approximately 1.4 million persons arrested for dwi.

What is DWI?

DWI is an acronym that stands for the words Driving While Intoxicated. It is referred to the following:

Drinking alcohol and driving,

Using prescription drugs and driving; and

Using illegal drugs and driving

The blood of these victims are usually tested to prove that their blood contains high contents of alcohol, prescription drugs and illegal drugs before they are being charged.

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Alcohol can die of liver cancer.

Answers

The risk of dying rises dramatically if you have liver cancer (hepatocellular carcinoma) or cirrhosis and drink alcohol.

a patient who is suspected of being hypoxic and is breathing adequately should be given supplemental oxygen with a:

Answers

A patient who is suspected of being hypoxic and is breathing adequately should be given supplemental oxygen with a: Non - rebreathing mask

How to give emergency oxygen?

When someone is said to be hypoxic, it simply means such a person has low levels of oxygen in his/her body tissues. This low levels of oxygen causes symptoms like difficulty breathing, rapid heart rate, restlessness, bluish skin, e.t.c

In conclusion, we can say that the patient should be given supplemental oxygen with a Non - rebreathing mask.

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A study is published saying that eating broccoli disrupts sleep, while another study says that eating broccoli enhances sleep. Which of the following does this most resemble

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A study is published saying that eating broccoli disrupts sleep, while another study says that eating broccoli enhances sleep. This most resemble current research on coffee.

What does caffeine stimulate?

Caffeine is a potent Central Nervous System (CNS) stimulant, as it increases mental and alertness activity and stimulates the respiratory center. It also reduces fatigue and can increase the ability to perform certain tasks.

That's why caffeine is very researched because it stimulates the nervous system and increases mental and respiratory processes.

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as a woman enters the second stage of labor, which would the nurse expect to assess?

Answers

In the second stage of labor, the nurse has to check the heartbeat of the fetus.

What is labor?

The term labor is the process by which a woman gives birth to baby. Labor involves contractions which are usually painful to the woman.

As a woman gets into the second stage of labor, it is expected that the nurse has to check the heartbeat of the fetus.

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ich topics and guidelines fall into four main categories:

Answers

The ICH has four main guidelines that are based on the quality, safety, efficacy and multidisciplinarity of clinical studies (Good Clinical Practices - BCP).

What is ICH?

Is an international standard of ethics and scientific quality for

designingconductingrecording and reporting

trials involving the participation of human subjects. Compliance with this standard provides a public guarantee that the rights, safety and well-being of trial participants are protected, consistent with the principles that have their origin in the Declaration of Helsinki, and that clinical trial data have credibility.

With this information, we can conclude that the ICH has four main guidelines that are based on the quality, safety, efficacy and multidisciplinarity of clinical studies (Good Clinical Practices - BCP).

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Let's say an 11 year old goes to the doctor for a normal check up. During the check up, the doctor weighs the girl and also measures her height. If she weighs 106 pounds and stands at 5ft tall, is she overweight or at a normal weight?
(will mark brainliest)​

Answers

Answer:

normal weight

Explanation:

im 5'2 amd weigh 132 and they said I wasnt overweight.

Which is true regarding electronic euthentication of medical record entries

Answers

A true statement about electronic authentification of medical record entries is that it is recognized by accrediting bodies.

What is a characteristic of electronic medical record authentification?

Medical records are now able to be authenticated electronically in order to reduce the time between a doctor requesting for these records, and the records being delivered.

As a result, it is recognized by accrediting bodies for its contribution to medicine.

Options for this question are:

A. recognized by accrediting bodies.

B.Does not hold the author of the entryaccountable

C. Is disadvantageous to medicine.

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How much blood does a microtainer/micro collection tube hold?

Answers

The microtainer/micro collection tube holds between 250 and 500 μl of blood.

What is a Collection tube?

This is often used in the laboratory and comprises of a plastic reservoir and a lavender color-coded closure.

The microtainer/micro collection tube holds about 250 and 500 μl of blood which is used for diagnosis etc.

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What is the correct definition for individual team sports?
OA. Sports in which only one player per team competes at a time, with
individual scores counting toward the team score.
B. Sports consisting of more than one player on the field or court at a
time.
OC. Sports that are less recognized than more popular sports such as
baseball and soccer.
D. Sports in which only one player competes at a time, for individual
points only.

Answers

Answer:

Sports in which only one player per team competes at a time, with individual scores counting toward the team score.

Explanation:

Examples include track and swimming.

For an individual with an open fracture of the leg, what would be an appropriate action?
A. Keep the person walking.
B. Apply Heat.
C. Call 911.
D. Start CPR

Answers

the answer is c, call 911

For an individual with an open fracture of the leg, an appropriate action to call 911.

what is fracture ?

A fracture can be defined as a broken bone which can range from a thin crack to a complete break.

Bone fracture occur crosswise, lengthwise, in several places, or into many pieces and it happen when a bone is impacted by more force or pressure than it can support.

It can increases intense pain when the initial injury occurs. It may become worse when you move or touch the injured area.

Other potential symptoms include a snap or grinding sound when the injury occurs, swelling, redness, and bruising in the injured area. difficulty supporting weight with the injured area

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Which of these strategies could best help you manage stress associated with
negative peer pressure?
A. Think about your values and beliefs, but do not speak about them.
B. Choose friends who pressure you to question your values and
beliefs.
C. Choose friends who encourage you to do well.
D. Find friends who are popular with other peers.

Answers

The correct answer is c I believe

Choose friends who encourage you to do well is the best strategy which could best help you manage stress associated with negative peer pressure. Thus, the correct option is C.

What is Negative peer pressure?

Negative peer pressure is when someone who is a friend or a part of a group we belong to makes us feel that we have to do something to be accepted. It is the negative peer pressure which we usually think of when the phrase peer pressure is used.

Negative peer pressure is related to influencing bullying behaviors, drinking alcohol, drug addiction and negative body image, all of which are harmful to a child or the young person's wellbeing.

Choosing friends who encourage us to do well is an important strategy which could best help a person to manage stress associated with negative peer pressure.

Therefore, the correct option is C.

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are sunglasses allowed at school on really hot UV rays and days

Answers

The need for pupils to be protected from sun exposure in schools is so critical that the California legislature took the time to establish a law giving students the legal right to bring sunscreen and wear sun-protective apparel to school.

What are sunglasses?

Sunglasses, often known as sun glasses, are a type of protective eyewear meant to shield the eyes from strong sunshine and high-energy visible light.

When heading to PE, recess, or drop off/pick up, children are allowed to wear sunglasses and hats to protect themselves from the sun. Hats and sunglasses are only permitted outside the building, according to the Dress Code. At no point are flip flops permitted. If they wear sandals to school, children are encouraged to bring tennis shoes to PE. When the child's arm is down at his or her side, the hemlines of shorts and skirts must not be higher than the child's fingertips.

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the patient has a significant visual impairment (category 2) due to astigmatism in the left eye. it is corrected with glasses. the right eye has normal vision. what icd-10-cm code(s) is/are reported?

Answers

The icd-10-cm codes that are reported will be H52.202 and H54.52.

What is astigmatism?

Astigmatism is when the curvature of the eye causes blurred distance and near vision.

In this case, the icd-10-cm codes that are reported will be H52.202 and H54.52. This implies the unspecified astigmatism left eye and low vision.

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a 78-year-old patient who had knee replacement surgery 2 days ago goes into cardiac arrest. which underlying cause should be given priority consideration?

Answers

Anemia should be given priority consideration as the underlying cause of the cardiac arrest.

What is Anemia?

This refers to the condition in which there is insufficient red blood cells in the distribution of oxygen to parts of the body.

This leads to catecholamine being released which results in high heart rate and in severe cases cardiac arrest.

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what is taste buds? write down their functions?

Answers

Answer:

Taste buds are sensory organs that are located on our tongue and let us feel tastes that are sweet, salty, sour, and bitter. Taste receptor cells, also known as gustatory cells, are found in taste buds.

[tex]\huge\purple{Hi!}[/tex]

Taste buds are sensory organs that are found on your tongue and allow you to experience tastes that are sweet, salty, sour, and bitter.The function of taste buds is to detect the various tastes like sweetness, saltiness, sourness and bitterness of food.

what is physical education?​

Answers

Explanation:

Physical Education is an element of an educational curriculum concerned with bodily development, physical health and wellness, strength, physical co-ordination, and agility

An element of an educational curriculum concerned with bodily development, physical health and wellness, strength, physical co-ordination, and agility

An educational posses that physical activities require skills and training

A nurse is caring for a patient who has been taking an antiepileptic drug for several weeks. The nurse asks the patient if the therapy is effective. The patient reports little change in seizure frequency. What will the nurse do?.

Answers

Answer:

contact the provider to request an order for serum drug levels.

Explanation:

if medication therapy is not effective, it is important to measure serum drug levels of the medication to determine whether therapeutic levels have been reached and to help monitor patient compliance.

i hope someone can help me here please don't answer nonsense!​

Answers

Answer:

This is only an example of a poster that I had previously done.

Explanation:

Use your career ideas :)

Hope this helps you just to get started...

a nurse is caring for a newborn client who is diagnosed with myelomeningocele. which nursing intervention would protect the newborn from injury?

Answers

The best intervention to protect the newborn from injury is to place the newborn in a prone or lateral position.

What is myelomeningocele?

Myelomeningocele is the most serious type of spinal disorder in babies.

With this condition, a sac of fluid comes through an opening in the baby's back. Part of the spinal cord and nerves are in this sac and are damaged.

Thus, when a nurse is caring for a newborn client who is diagnosed with myelomeningocele,  the best intervention to protect the newborn from injury is to place the newborn in a prone or lateral position.

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Read the sample student paragraph that addresses a counterclaim.Some claim that the Internet both invades and compromises ones right to privacy. However, this is ridiculous. The Internet is only as invasive as one allows it to be, particularly since there are laws to protect peoples privacy. Exercising caution when supplying personal information online is the most vital step in protecting ones privacy. Any information you do not feel comfortable sharing online should not be shared, and sensitive information should only be provided to trusted organizations. Additionally, some states have already enacted privacy laws that model the Federal Privacy Act of 1974, ensuring that information collected for one purpose may not be usedor soldfor other purposes without first notifying the individual to whom the data belongs. The first and most important protector of an individuals information is that individual. People whose personal information is not properly protected only have themselves to blame.What is the counterclaim in this paragraph?Personal information should only be shared with trusted organizations.It is important to be cautious when supplying personal information online.The Internet both invades and compromises an individuals right to privacy.It is each individuals responsibility to protect ones private information. name this country that suffered the horrific effect of an atomic bomb during ww2 3xy - + 4x for x = -2, y = - and = 6? Helppp! Which linear inequality is represented by the graph When independent stock transfer agents are not employed and the corporation issues its own stock and maintains stock records, canceled stock certificates should Multiple Choice Not be defaced but be segregated from other stock certificates and retained in a canceled certificates file. Be destroyed to prevent fraudulent reissuance. 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Calculate the unpaid balance, finance charge, and new balance using the unpaid balance method. Note: Interest rate is given as a monthly rate Previous balance:$179.32Payments/credits:$85.00Unpaid balance:$Monthly rate:1.25%Finance charge:$New purchases=$117.42New balance=$ Mathis is working on a dissertation involving the religious practices of the Aztec empire he wants to visit areas that are related to his field of study which regions of North America would be the best place for her to visit show that 8/15 plus 3/10 equals 5/6 Read this excerpt from "The World on Turtle's Back."Without knowing it, the right and left-handed twins built balance into the world. The plant-eating animals createdby the right-handed twin balanced out the meat-eating animals created by the left-handed twin. And so the worldthrived, and this was good.Which statement best describes the purpose of this excerpt?to describe who created plant- and meat-eating animalsto explain that some animals are good and others are evilto explain how balance came to exist in the natural worldto describe two different kinds of animals found in the world I need help with dis math problem (img included) Margo borrows $600, agreeing to pay it back with 7% annual interest after 8 months. How much interest will she pay? Mrs. Reynolds is in her Medicare initial coverage election period (ICEP) and the date of her entitlement to Part A and B has already occurred. Mrs. Reynolds has just signed up for a Medicare Advantage plan on the second of the month. She is leaving for vacation in two weeks and wants to know if her new coverage will start before she leaves. What should you tell her? Which substance is an example of organic matter? Look at the text below and correct the punctuation mistakes. There are 3 in total. 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