Suppose a researcher introduces a mutation into the glucosidase domain of the mammalian glycogen debranching enzyme. The mutation inhibits the activity of the glucosidase but does not affect the other functions of the enzyme. The researcher then introduces the mutated enzyme into mammalian cells that do not express wild type glycogen debranching enzyme. Predict the effect of the mutation on glycogen metabolism.

Answers

Answer 1

Answer:

cells will have glycogen molecules with branches of a single glucose residue

Explanation:

Glycogen debranching enzymes are proteins that catalyze the removal of branching from glycogen, which is a multibranched polysaccharide composed of glucose units and serves as a form of energy storage. These enzymes have two catalytic activities on a single polypeptide chain: glucosyltransferase and glucosidase activities, which are both required for glycogen breakdown. Glycogen degradation requires both glycogen phosphorylase and glycogen debranching enzymes. First, a glycogen phosphorylase acts to digest a glycogen branch down to four glucose residues. Subsequently, the debranching enzyme through its glucosyltransferase activity acts to transfer three glucose residues to a nearby branch of the glycogen chain. Finally, through its glucosidase activity, the debranching enzyme cleaves the remaining α-1,6 linkage in order to release free glucose.


Related Questions

difference between chromosomes and DNA​

Answers

Answer:

The DNA in a human body is organized into many stretches of genes. Proteins attach themselves to these stretches and coil them so that they form chromosomes. These stretches are very important in the formation of an organism. Do you know why?

Which of these would have the lowest kinetic energy?

Answers

Are there options too? If yes, then plz provide the options too, the next time you ask :) . Solids would have the lowest kinetic energy and gases have least kinetic energy.

You didn’t provide choices to choose from, but Solid particles have the least kinetic energy while Gas particles have the greatest amount

click on the link below to see the primate family tree diagram. Which of the following statements is true?

Answers

Answer:

biology is amazing it contains some reproductive topics

Orangutans evolved from an ancestor they share with gorillas is true regarding primate family tree diagram. This means that orangutans and gorillas have a common ancestor. Option C is the correct answer.

Evolution is the process through which species change over time. It occurs through the accumulation of genetic variations and natural selection. The primate family tree shows the evolutionary relationships between different primate species, including orangutans and gorillas. Option C is the correct answer.

Orangutans and gorillas share a common ancestor in their evolutionary history. This means that at some point in the past, there was a species that gave rise to both orangutans and gorillas. Over time, as the common ancestor of orangutans and gorillas diverged into separate lineages, each species developed its own unique traits and characteristics. Despite their distinct characteristics, orangutans and gorillas still share certain genetic similarities due to their common ancestry. These similarities can be observed in their DNA sequences.

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The complete question is, "Which of the following statements is true regarding primate family tree diagram?

A. Orangutans evolved from lesser apes and Old World monkeys.

B. Gorillas evolved from orangutans.

C. Orangutans evolved from an ancestor they share with gorillas.

D. Gorillas are more closely related to lesser apes than to chimpanzees."

Transcription and Translation Questions Note: Answer the following questions without taking start codon into consideration. 6. The template DNA sequence is 5’ ACCTGAGTC 3’, what is the transcribed mRNA sequence from 5’ to 3’?

Answers

3’ UGGACHCAG 5’ is the answer.

The the below the states five clemos demented by A. 1) and
with their tennie numbers, entro numas, amber of electrons i
mass numbers. Study the table and answer the questions that follow
Home


number
Number of
metros
Number of
electron
Mass
nonbey
Element
A
12
12
19
24
/
H
7
7
14
10
C
11
13
11
18
35
D
17
18
©
12
22
10
Write the element(s) that is/are
cations)
(1) anionis)
neutral;
(10) isotope(s)
17 mark

Answers

Answer:

which class ? this has two answer

Two species have homologous structures. What do these homologous structures show about the evolutionary relationship between the two species?

Answers

Two species have homologous structures. What do these homologous structures show about the evolutionary relationship between the two species? (3 points) The homologous structures show that the two species followed up the evolutionarypath up to the structure. They may have branched off right after that trait.

What would be most likely to happen if some of the proteins Ik one of the photo systems were to change shape due to a drop in cell pH?
A. A decrease in the formation of NADPH
B. An increase in the formation of NADP+
C. A decrease in chlorophyll production
D. An increase in sugar production

Answers

Answer:

Option A

Explanation:

If some proteins in one of the photosystems undergo change in their shape due to a drop in pH of cell, they will not perform their activity. Due to this, there will be a decrease in the formation of NADPH ( that is less reduction of NADP due to blockage in the transport of electron).

Which of the following statements about continuous variables is
A. continuous variables must lie between a clearly defined interval
B. continuous variables may be restricted to positive values
C. continuous variables will never be nonzero
D. continuous variables must always be restricted to positive values

Answers

Answer:

I think it's A

must lie btn a clearly defined interval

Continues variable must be between a clearly defined the interval about continuous variables. Thus,option A is correct.

What is continuous variables?

A continuous variables is define as a function which continuous varies in a given interval for instance, if a variable over a non-empty range of the real numbers is continuous, then it can take on any value in that range.

Types of continuous variables:

There are two types of continuous variables which are mentioned below:-

1:- Instant variable

2:- Ratio variable

Instant variable

A variable can be defined as the distance or level which are varies between given interval.

Ratio variable

Ratio variable is another type of continuous variables which has only one variation in given interval.

Therefore, continues variable must be between a clearly defined the interval about continuous variables. Thus, option A is correct.

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HELP ASAP I WILL GIVE BRAINLIST

An unknown solution has a pH of 7.1. Which of these chemicals is likely to increase the pH the most when added to the solution?

HF

KOH

NH3

HNO3

Answers

Answer:

It is most likely KOH

Explanation:

NH3 is classified as a weak base so I'd suspect that to be incorrect although it does have a higher pH

The chemical that is likely to increase the pH the most when added to the solution is KOH. The correct option is B.

What is pH?

pH is the scale for the measurement of acidity and the basicity of any solution. pH is a scale from 1 to 14. The lowest pH will be highly acidic and the highest pH will be the highest basic.

The lowest the pH, it will donate the highest hydronium ions, and with the highest pH, it will dissociate completely into the solution. KOH dissociates completely into ions.

KOH or potassium hydroxide is a strong base. When the base is added to a solution, it increases its basicity. So it will increase the pH of the solution. All others are acids that will lower the pH of the solution.

Thus, the correct option is B. KOH.

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What allows humans to have different traits from each other?
A. They store DNA in different places.
B. They have different genes.
C. They have different haploidnumbers.
gling
D. They have different number
Ichromosomes.
SUBMIT

Answers

Answer:

B. They have different genes.

Explanation:

Direct counts of cells in liquid samples can be performed using a Petroff-Hausser counting chamber. Research this method and describe how it compares to the viable plate count method of determining the number of CFU in a sample.

Answers

The viable plate count is the most commonly used method to estimate the number of viable cells in a sample; while the Petroff-Hausser counting chamber is a direct microscopic count method generally used for counting bacteria and sperm cells.

The Petroff-Hausser counter is a counting chamber used to count microorganisms and cells (e.g., bacteria and spermatic cells) under the microscope.

The Petroff-Hausser counter chamber is divided into 25 large squares which are in turn divided by double lines. Moreover, within each large square, there also are 16 small squares divided by single lines.

Petroff-Hausser counting chambers are often used to directly determine the number of bacteria in a culture or liquid medium. Petroff-Hausser counting chambers are used to count the number of cells in a given volume of culture liquid by observing 10 to 20 microscope fields.

The viable plate count, also known as simply plate count, is the most commonly used procedure to estimate the number of viable cells in a sample.

The viable plate count method consists in obtaining serial dilutions of a sample having viable microorganisms/cells which are plated onto a growth medium.

This method (viable plate count) can be used to determine the number of actively dividing cells.

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What is Anatomy and physiology

Answers

Answer:

Anatomy: The branch of science concerned with the bodily structure of humans, animals, and other living organisms, especially as revealed by dissection and the separation of parts.

Physiology: The branch of biology that deals with the normal functions of living organisms and their parts.

Explanation:

Anatomy = The science that deals with the form and structure of organic bodies; anatomical structure or organization is Anatomy.

Physiology = A branch of biology that deals with the functions and activities of life or of living matter (as organs, tissues, or cells) and of the physical and chemical phenomena involved is Physiology.

Hope it will help:)❤️

A polypeptide can be made up of a chain of as many as _______ amino acids.

Answers

Answer:

A polypeptide can be made up of a chain of as many as 50 amino acids.

Compared with a eukaryotic cell, a prokaryotic cell Select one:______
a. lacks organelles beyond ribosomes.
b. is larger.
c. does not require energy.
d. is not living.
e. has no method of movement.

Answers

I believe A) would be the most correct answer in this case. However, the most significant difference between eukaryotes and prokaryotes is that eukaryotic cells contain a nucleus, while the latter does NOT.

B) is incorrect because prokaryotic cells are typically smaller than eukaryotic cells. Think bacteria and other microorganisms.

C) is incorrect because, well, energy is…

D) False, a non-living microorganism would be considered a prion or virus before prokaryote.

E) Many prokaryotic cells actually contain flagellum or cilia for transport.

Let me know if you have other questions — good luck.

Sophia
Which of the following represents the correct flow of information during
homeostasis?
Home
a.) Integrator - Sensor - Effector
O b.) Sensor - Integrator - Effector
Hi
WHAT'S
oc.) Sensor - Effector - Integrator
Welcome to
allows your
o d.) Effector + Integrator + Sensor
1. Homeo
2 Sensors

Answers

Answer:

b.) Sensor - Integrator - Effector

Explanation:

During homeostasis, our body sense change that occur in the external environment through sensors. These sensors sends the information to integrator or the control center where the information is analyzed. After analysis, the instructions are send to the effectors to take action against the change which is occur in the external environment of our body so the correct order of homeostasis is Sensor - Integrator - Effector.

What was the name of your fish sample, according to the restaurant menu?
Types of Sashimi (slice of raw fish) listed on the restaurant menu:
1. Escolar – Super white tuna
2. Maguro – Big eye tuna
3. Hamachi – Yellowtail
4. Tai – Red snapper
5. Nama Sake – Salmon
6. Saba – Mackerel Fish

Answers

normally, yellowtail and salmon is served as sashimi but im not sure I don't really get the question lol

Khi glycine gắn vào repressor và làm cho repressor gắn vào NST tế bào vi khuẩn, đưa tới kết quả:
a/ Ngừng sự sinh tổng hợp glycine
b/ Ức chế tế bào vi khuẩn phân chia
c/ Phân hủy glycine
d/ Tạo ra protein repressor

Answers

Answer:

b

Explanation:

Match the terms in column B to the descriptions in column A.

Column A:

1. Connects the larynx to the main bronchi
2. Includes terminal and respiratory as subtypes
3. Food passageway posterior to the trachea
4. Covers the glottis during swallowing of food
5. Contains the vocal cords
6. Indentation on the lung where the lung root structures enter and exit
7. Pleural layer lining the walls of the thorax
8. Site from which oxygen enters the pulmonary blood
9. Connects the middle ear to the nasopharynx
10. Pleural layer in contact with the surface of the lung
11. Increases air turbulence in the nasal cavity
12. Separates the oral cavity from the nasal cavity

Column B:
a. alveolus
b. bronchiole
c. conchae
d. epiglottis
e. esophagus
f. hilum
g. larynx
h. palate
i. pharyngotympanic tube
j. parietal pleura
k. trachea
l. visceral pleura

Answers

Answer:

1. Connects the larynx to the main bronchi k. trachea

2. Includes terminal and respiratory as subtypes b. bronchiole

3. Food passageway posterior to the trachea. e. esophagus

4. Covers the glottis during swallowing of food d. epiglottis

5. Contains the vocal cords g. larynx

6. Indentation on the lung where the lung root structures enter and exit f. hilum

7. Pleural layer lining the walls of the thorax j. parietal pleura

8. Site from which oxygen enters the pulmonary blood a. alveolus

9. Connects the middle ear to the nasopharynx. i. pharyngotympanic tube

10. Pleural layer in contact with the surface of the lung l. visceral pleura

11. Increases air turbulence in the nasal cavity c. conchae

12. Separates the oral cavity from the nasal cavity h. palate

Explanation:

1. The trachea is between the main bronchi and the larynx. It has semicircular rings of cartilage. The function of this organ is to conduct the air from the larynx to the primary/main bronchi.

2. After the primary (main), secondary, and tertiary bronchi, the terminal and the respiratory bronchioles come. They also conduct the air towards the alveoli so that the oxygen can enter the blood. The diameter of the bronchi terminal is smaller than the bronchi, and the diameter of the respiratory bronchi is smaller than the previous ones.

3 and 4. The esophagus is not part of the respiratory system. It is a tube that belongs to the digestive system since food has to pass through it to go to the stomach. The esophagus is posterior to the trachea, and the epiglottis closes the entrance to the larynx when we swallow to stop food from going to the lungs.

5. The vocal folds are in the larynx. This one is between the trachea and the pharynx. There are two types of vocal folds, the true and the false vocal folds. Both of them vibrate when air passes through them, allowing us to speak and make different tones.

6. The hilum is the lungs section where the bronchus, the pulmonary artery, and the pulmonary vein enter the lung. It is an indention that is in the middle part of the lungs.

7 and 10. The pleura has two sides, the parietal one and the visceral one. The first one is in contact with the lungs and the second one with the thorax's walls. Between them, there is a space called the pleural cavity. The cavity has fluid that allows the movement of the two pleurae. As a result, the lungs can move and fill with air.

8. After the respiratory bronchioles, we have the alveolar duct. The alveolar ducts lead to alveolar sacs. The alveolar sacs has the alveolus. They are thin walls that are in contact with capillaries. When the air is there, the oxygen passes through the thin walls. Then it goes through the capillaries' walls and into the blood.

9. The pharyngotympanic tube is also known as the Eustachian tube. It connects the middle ear to the nasopharynx. Its function is to regulate the pressure in the ear.

11. The conchae are in the nasal cavity. They are three projections in the nasal cavity, the inferior one, the middle one, and the superior. Their function is to increase the surface of the nasal cavity so that more air can enter with every inspiration. As they are projections, they modify the laminar airflow producing a turbulent flow.

12. The palate is between the nasal cavity and the oral cavity. It has two parts, the soft palate, and the hard palate. The palate helps in the production of certain sounds and divides the nasal cavity from the mouth.

The history of life has been punctuated by several mass extinctions. For example, the impact of a meteorite may have wiped out most of the dinosaurs and many forms of marine life at the end of the Cretaceous period. Fossils indicate that plants were less severely affected by this mass extinction. What adaptations may have enabled plants to withstand this disaster better than animals

Answers

Answer:

Due to dormancy.

Explanation:

Plants have an advantage in surviving mass extinction because Plant seeds can remain dormant for many years in the soil without damaging and comes out from the soil when the conditions of the external environment become suitable. Plants can remain in dormant condition for a large period of time while on the other hand, animals have no such type of advantage so that's why plants survive mass extinction.

Which allows materials to enter and exit the nucleus?


pore

nucleolus

chromatin

cell wall

Answers

Answer:

a pore allows materials to enter and exit the nucleus

Nuclear pores allow materials to enter and exit the nucleus.

Which is the only element in group 1 on the periodic table that forms covalent bonds?

hydrogen
lithium
potassium
sodium
.

Answers

Answer:

Hydrogen

Explanation:

Hydrogen is the only nonmetal in group 1, therefore it is the only element in group 1 that forms a covalent bond.

Answer:

A.

Explanation:

Which of the following sequences on a DNA molecule would be complementary to
GCTTATAT?
A.TAGGCGCG
B.COD ATCCGCGC
C.KUCGAATATA
D.TGCCTCTC
E.None of the above

Answers

E. None of the above because I’m smart

Many anti-evolutionists believe that since science doesn't have answers for all questions; scientific conclusions are not necessarily correct. This attitude reflects a failure to understand the nature of science. What is the general nature of scientific thinking? In what way is science "self correcting"?

Answers

Answer:

In science, accepted theories do not represent absolute truths. A scientific theory is accepted when there is much evidence available that support its statements, but new lines of evidence can modify original presumptions  

Explanation:

A scientific theory is a plausible explanation of a particular phenomenon of the natural world, which has been many times tested and verified by using the scientific method. The accepted theories are progressively modified (or even overturned) as new lines of evidence emerge. In consequence, a scientific theory is composed of statements that we consider as truths regarding the available evidence, but we have no absolute certainty that such statements are true. The ability to self-correct is fundamental in science and it happens when we discover that the original statements of a scientific theory were wrong, thereby new lines of evidence allow us to correct the error and/or develop new scientific theories.

what kind of services are provided in travel and tourism​

Answers

Answer:

Tourism and travel-related services include services provided by hotels and restaurants (including catering), travel agencies and tour operator services, tourist guide services and other related services.

An increase in the biodiversity of an ecosystem leads to an increase in its productivity.

True
False

Answers

Answer:

true

Explanation:

Bacterial strain A (met , his-, arg ) is mixed with bacterial strain B (met-, his , arg-), grown in complete media, then plated on minimal media supplemented with histidine. Bacteria grows on the plate, which indicates that ________.

Answers

Answer:

Plate has all the essential nutrients that is required by the bacteria.

Explanation:

Bacteria grows on the plate, which indicates that the plate has all the essential nutrients that is required by the bacteria. Bacteria needs a type of media for its growth which contains all the necessary items which plays a key role in its growth and development. This plate has a media that contains food which the bacteria use for its growth and development so that's why we can say that  plate has all the essential nutrients that is required by the bacteria.

In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3’UTR of the mRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a DNA methyltransferase (DNMT) which is an enzyme that methylates DNA when the protein is in its active form.
A) In a lung cancer cell line, the p101 protein is overly active leading to misregulation of gene expression. In these lung cancer cells which of the following would be a correct prediction in regards to miR-5? [choose ALL that apply, note that incorrect selections will deduct points]
A) The gene encoding miR-5 is in a region of chromatin with hypoacetylation
B) The gene encoding miR-5 is in a region of chromatin with hyperacetylation
C) The gene encoding miR-5 in a region of euchromatin
D) The gene encoding miR-5 in a region of heterochromatin
E) The miR-5 transcript is translated at high levels
F) The miR-5 transcript is activating translation of the UCD gene
B) A different lung cancer cell line is found to have significantly decreased amounts of DNA methylation. Which of the following could explain why there is decreased DNA methylation in this cell line? [choose ALL that apply, note that incorrect selections will deduct points]
A) increased amounts of the p101 protein due to low levels of miR-5
B) increased amounts of the UCD protein due to high levels of miR-5
C) decreased amounts of the UCD protein due to low levels of miR-5
D) the absence of the UCD protein due to miR-5 inhibiting translation of the UCD mRNA transcript
E) the absence of the p101 protein due to miR-5 inhibiting transcription of the p101 mRNA transcript

Answers

Answer:

A) A) The gene encoding miR-5 is in a region of chromatin with hypoacetylation.  

D) The gene encoding miR-5 in a region of heterochromatin.

B) D) the absence of the UCD protein due to miR-5 inhibiting translation of the UCD mRNA transcript

Explanation:

MicroRNAs (miRNAs) are small regulatory RNA sequences (approximately 20-24 nucleotides in length) that regulate gene expression by RNA interference (RNAi) mechanisms. These sequences (miRNAs) bind by base complementarity to messenger RNAs and thus inhibit protein translation and/or trigger mRNA degradation. In this case, miR-5 binds to the 3’UTR of the mRNA transcript of the UCD gene, thereby inhibiting/slowing protein UCD synthesis. The UCD protein is an allosteric regulator that binds and activates the expression of the p101 protein, thereby the miR-5 RNAi pathway also indirectly decreases the expression of the p101 gene. Moreover, hypoacetylation is an epigenetic mark generally associated with gene silencing (heterochromatin is a transcriptionally inactive state of chromatin).

Some of the largest mountains in the world, including the Himalayas, occur where

Select one:

a.
two oceanic plates diverge.


b.
two continental plates converge.


c.
an oceanic and a continental plate diverge.


d.
an oceanic and a continental plate converge.

Answers

Answer:

b. two continental plates converse

Compare and contrast the two upper layers of the mantle?

Answers

Answer:

Both the lithisphere and asthenosphere are the part of Earth and are made of similar material. Lithosphere is made up of Earth's outermost layer, the crust, and the uppermost portion of the mantle. In comparison, the asthenosphere is the uppermost portion of Earth's mantle. Which is also the middle layer of Earth.

5. Imagine that you encounter two color morphs of S. marcescens in natural environment. If you do not have any prior knowledge on the prodigiosin synthesis pathway of these Serratia species, will you consider the red and white Serratia colonies as one species or two species? Do you think we should designate species based on morphological traits or genetic differentiation? Without limiting to the S. marcescens experiment, provide evidence and example to support your claim.

Answers

Answer:

According to the given question that without prior knowledge on the prodigiosin synthesis pathway of these Serratia species, and we experience two different color morphs of the species. So, there is given or known preliminary morphological basis we will consider them different two different colonies. These can be identify only after genetically identify or study.

The morphological characterstics of the organism and the genetic identification both are equally important. So Giving any one more importance over other is not logical.

Morphologically we can differentiate the color of the colonies of mutants. The mutant serratia sp. are  known for eficient biosynthesis of prodigiosin, Thus on the basis of color characteristics of their colonies when grown on peptone glycerol medium we can identify.

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Personality disorders (like antisocial personality disorder or borderline personality disorder) are characterized by Group of answer choices Inflexible and enduring behavioral patterns that impair social functioning Persistent anxiety or depression An elevated level of autonomic nervous system arousal Hallucinations or delusions Father is four times the age of his daughter. If after 5 years, he would be 3 times of daughter's age, then further after 5 years, how many times he would be of his daughter's age? What is the format of this proof?Given: AB = BCProve: B is the midpoint of AC.BO two-column proofO one-paragraph proofO flowchart prooftwo-paragraph proofAB = BCgivenAB a BCdef. of a segs.Bis the midpoint of ACdet of midpt A textbook store sold a combined total of 473 chemistry and sociology textbooks in a week. The number of sociology textbooks sold was 59 less than the number of chemistry textbooks sold. How many textbooks of each type were sold? Which equation is the inverse of y = 16+ 1?Choices In terms of the hierarchical scales of biological organization, __1__ are a very large scale, __2__ are a very small scale, and __3__ is between them. 3. (a) Determine the sum of the interior angles of the polygon below.(b) Determine the measure of the angle indicated by the letter, a, in the polygon. The number N is the smallest positive integer with the sum of its digits equal to 2020. What is the first (leftmost) digit of N? Please hurry I will mark you brainliest What is the value of p in the equation of the line px + 2y + 8 = 0, so that the x-intercept is 4? What are the proper steps to take leading to CPR?Put the statements below in the correct order by clicking and dragging the arrows.1. Tell someone to call 911 and get an AED2. Check if the scene is safe3. Check for breathing4. Tap and shout5. Shout for help If a house is worth $125,000 and depreciates by 7.5% per year, how much is it worth in two years Reread the first two paragraphs of the passage.How does this opening section develop the central idea of the passage?It explains how Douglass comes to understand that white people take advantage of ignorance to keep black people enslaved.It shows that Douglass is a quick learner and sets the stage for the passage's exploration of how Douglass learns to read.It shows the mean-spirited attitude of Mr. Auld and sets the stage for the central idea: the cruelty of white slaveholders.It describes Douglass's relationship with Mr. and Mrs. Auld and introduces the central idea: Douglass's resentment of Mr. and Mrs. Auld. A window is to be built in the shape of a rectangle surmounted by an isosceles triangle. The area of the window must be 6 square meters. Use Lagrange Multipliers to find the width and height of the rectangle for which the perimeter of the window will be as small as possible can i get some help please Chip is a veteran who fought in Desert Storm. He has just retired from the military. He has been told he qualifies for a property tax exemption based on his military service during wartime. Which exemption applies to Chip? Calfornia Homeowner's Exemption The Mello-Roos Community Facilities Act California Military Exemption The Street Improvement Act why HDI should high? What is the measure of 513The probabilities that three men win their respective races are 1/3,3/5and 3/4.what is theprobability thata) all of them win their races)b) only one of them win his race? Robi bought a toy car for $x. He sold it at a loss of 10%. Find the expressionfor the selling price. A study examines the relationship between being a registered nurse (yes/no) and passing a cultural competency exam (yes/no) among a group of 987 randomly selected employees at your hospital. What test would be appropriate to determine if there is an association